Grey's Anatomy is a hospital drama that focuses on Meredith Grey (Ellen Pompeo), one of several first-year surgical interns, (now first year resident) at a Seattle, Wash., hospital. Along with her colleagues, Meredith struggles to maintain relationships while staying sharp at her new job. The professional roles and real lives of a diverse group of surgeons collide unexpectedly in this Golden Globe-winning ABC television drama. As an intern at prestigious Seattle Grace Hospital, Meredith Grey (Ellen Pompeo) tries hard to live up to the reputation of her legendary surgeon mother while hiding the fact that her mom now suffers from Alzheimer's disease. As if life weren't complicated enough, Meredith also falls for her boss, Derek Shepherd (Patrick Dempsey), a surgical resident recently relocated to Seattle from New York. Meredith's friend and rival Cristina Yang (Sandra Oh) finds herself in a similarly taboo romance with Preston Burke (Isaiah Washington), Derek's chief competition for the title of chief resident. As for Meredith and Cristina's fellow interns -- Isobel "Izzie" Stevens (Katherine Heigl), George O'Malley (T.R. Knight), and Alex Karev (Justin Chambers) -- they've got problems of their own. Izzie doesn't want to be judged for her underwear-model past; Alex is better at bedding the ladies than bedside manner; and George can't get any of the women around him to see him as anything but a cuddly friend. All five interns answer to the roar of senior resident Miranda Bailey (Chandra Wilson), affectionately known as "the Nazi.